ImmunoCAP

Interpretation of Test Results

Whether the results are positive or negative, an ImmunoCAP test report holds great clinical value. On this page are two handy tools to help you interpret test results and consider management options based on the reported levels of specific IgE.

Results interpretation guide

You can use this guide to interpret ImmunoCAP Specific IgE blood test results. It shows a sample test report with explanatory text. Click on the highlighted areas for details on those sections of the report.

Click here to download a printable PDF version of this guide. You will need Adobe Acrobat Reader to view and print it.

Clinical implications

This chart shows clinical implications for patients tested with ImmunoCAP. Designated for those with respiratory symptoms, the options displayed here correspond to the specific IgE levels reported for the individual profile allergens.

Clinical Implications for Specific IgE Levels

Previous Reporting Range (kU_A/L)	New Reporting Range (kU_A/L)	Clinical Implications
<0.35	<0.10	Absent/Undetectable/Negative (Normal)
	0.10-0.35	For specialist use only: Clinical relevance undetermined
0.35-0.70	0.35-0.70	Low level of allergy, indicative of ongoing sensitization³
0.70-3.5	0.70-3.5	Moderate level of allergy, indicative of stronger ongoing sensitization³
3.5-17.5	3.5-17.5	High level of allergy, indicative of high-level sensitization
17.5-50	17.5-50	Very high level of allergy, indicative of very high-level sensitization
50-100	50-100	Very high level of allergy, indicative of very high-level sensitization
>100	>100	Very high level of allergy, indicative of very high-level sensitization

References

Yman L. Botanical Relations and Immunological Cross-reactions in Pollen Allergy. 2nd ed. Uppsala, Sweden: Pharmacia Diagnostics AB; 1982;2:9-10.
Nalebuff DJ. Use of RAST screening in clinical allergy: a cost-effective approach to patient care. Ear Nose Throat J. 1985;64:107-121.
Yunginger JW, Ahlstedt S, Eggleston PA, et al. Quantitative IgE antibody assays in allergic diseases. J Allergy Clin Immunol. 2000;105:1077-1084.

Management Options

Using the results reported by the ImmunoCAP specific IgE blood test, you can rule atopy in or out and guide the management of your patient’s symptoms. Depending on the symptoms and test results, you have a wide range of possible choices Click the links below to see potential options for treating patients with childhood diseases (CHDs), upper respiratory diseases (URDS), or lower respiratory diseases (LRDs).