Interpretation of Results

How do results correlate to symptom severity?
The higher the response value, the more specific IgE is in the sample. A high or low specific IgE level may not necessarily correlate to the degree of symptom severity, because each person’s symptom threshold varies.

How should I interpret specific IgE levels?
This chart lists IgE ranges as well as management options according to the degree of allergic response.

Click here to download a PDF file of this chart.

What do I do when the results are positive (ie, patient is allergic)?
You can use the information to confirm atopy and identify specific allergens to counsel for avoidance and guide effective medication selection. Allergy is a cumulative threshold disease.1 Symptoms of atopic illness are often triggered only after exposure to multiple allergens. The patient who is sensitized to more than one allergen crosses the symptomatic threshold only after a cumulative allergic load has been reached.1

Patients can find resolution of their symptoms through the avoidance of one or more allergens in order to diminish that cumulative load to a level at which symptoms don’t occur.2 With the specific quantitative results offered by the ImmuoCAP profiles, you can develop an effective management program to tailor avoidance measures as appropriate to reduce cumulative allergic load and guide appropriate treatment selection or referral.

Click here to learn more about managing allergic disease.

What do I do with a negative test result?
Specific IgE testing offers advantages when atopy is not involved. By ruling out an allergic etiology, the clinician can focus the evaluation on other possible causes (including anatomical, bacterial, medical, hormonal, and vasomotor)3 in order to select an appropriate treatment or make any necessary referrals. In addition, you can avoid prescribing costly non-sedating antihistamines, which are thought to be ineffective in non-atopic patients2 and are not indicated for use in this population.

Click here to learn more about managing non-allergic disease.

Can I use the results to perform immunotherapy treatments?
If immunotherapy is indicated, refer the patient to an allergy specialist.

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